L. Saveanu lab

when immunology meets cell biology

Immune receptors signaling in cancer and infection

We seek to understand how intracellular trafficking affects the activation and function of immune cells, including professional antigen-presenting cells and T cells. None of our results would be possible without innovative methods, including:

  • High-resolution time-lapse microscopy
  • Quantitative mass spectrometry of the dynamic association of proteins by proximity labeling
  • Animal models to study the immune response in cancer and infection.

These methods are used to generate or validate new hypotheses about how the immune system works.

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